| Autor: |
Kim Bok-Hee, Ryu So-Yeon, Yun Woo-Jun, Ahn Hye-Ran, Rhee Jung-Ae, Choi Jin-Su, Kweon Sun-Seog, Shin Min-Ho, Lee Young-Hoon, Nam Hae-Sung, Jeong Seul-Ki, Park Kyeong-Soo |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
BMC Public Health, Vol 11, Iss 1, p 94 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
1471-2458 |
| DOI: |
10.1186/1471-2458-11-94 |
| Popis: |
Abstract Background We investigated the association of cumulative smoking exposure and duration of smoking cessation with peripheral arterial disease (PAD). Methods The study population consisted of 2517 community-dwelling Korean men aged 50 years and older. Information on smoking characteristics such as smoking status, pack-years of smoking, and years since quitting smoking was collected using a standardized questionnaire. PAD was defined as an ankle-brachial index (ABI) less than 0.90 in either leg. Results The odds ratio (OR, 95% confidence interval) of PAD was 2.31 (1.20-4.42) for former smokers and 4.30 (2.13-8.66) for current smokers, after adjusting for other cardiovascular risk factors. There was a significant dose-response relationship between pack-years of smoking and PAD. Compared with those who had never smoked, the multivariate-adjusted ORs of PAD for smokers of 0.1-20.0, 20.1-40.0, and >40.0 pack-years were 2.15 (1.06-4.38), 2.24 (1.08-4.65), and 2.93 (1.41-6.09), respectively. There was a significant decrease in PAD risk as the years since quitting smoking increased. The multivariate-adjusted ORs of PAD for 11-20 and ≥21 years smoking cessation were 0.41 (0.19-0.86) and 0.49 (0.24-0.98), compared with current smokers. Conclusions Cumulative smoking exposure and duration of smoking cessation were significantly associated with PAD in middle aged and older Korean men. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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