| Autor: |
Hua LI, Yiyu ZHAO, Yating HU, Yong HAO, Hui HAN |
| Jazyk: |
čínština |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Pifu-xingbing zhenliaoxue zazhi, Vol 29, Iss 1, Pp 16-22 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1674-8468 |
| DOI: |
10.3969/j.issn.1674-8468.2022.01.004 |
| Popis: |
Objective To observe the efficacy of Q switch ruby laser combined with tranexamic acid for melasma and its effects on melanin metabolism. Methods A total of 60 patients with melasma were divided into three groups: Drug group (oral tranexamic acid 500 mg/day for six months), the laser group (Q switched ruby laser, once every 2 weeks for 2 months), combination therapy (laser plus tranexamic acid, same method and course of treatment as in single modality). Results Combination therapy significantly lowered Melasma Area and Severity Index compared to single treatment modality [(67.02±18.58)% vs. (53.13±20.66)% in laser and (53.97±18.48)% in drug group), both P0.05). After the treatment, levels of Tyr and MSH in the combination therapy were lower than that in the laser and drug groups, while MT levels was higher in the combination therapy than in the laser and drug groups (all P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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