Engineering transferrable microvascular meshes for subcutaneous islet transplantation

Autor: Wei Song, Alan Chiu, Long-Hai Wang, Robert E. Schwartz, Bin Li, Nikolaos Bouklas, Daniel T. Bowers, Duo An, Soon Hon Cheong, James A. Flanders, Yehudah Pardo, Qingsheng Liu, Xi Wang, Vivian K. Lee, Guohao Dai, Minglin Ma
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-019-12373-5
Popis: The success of engineered tissue depends on the integration of a dense vascular network to supply nutrients and remove waste products. Here the authors design high density microvascular meshes made through an anchored self-assembly mechanism, and use these meshes to support subcutaneous pancreatic islet survival in a mouse diabetes model.
Databáze: Directory of Open Access Journals