Autor: |
Cong-Cong Qi, Li-Ran Xu, Chang-Jia Zhao, Hai-Yan Zhang, Qing-Ya Li, Mei-Jun Liu, Ye-Xuan Zhang, Zhou Tang, Xiu-Xia Ma |
Jazyk: |
angličtina |
Rok vydání: |
2023 |
Předmět: |
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Zdroj: |
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-13 (2023) |
Druh dokumentu: |
article |
ISSN: |
1471-2334 |
DOI: |
10.1186/s12879-023-08575-4 |
Popis: |
Abstract Objective To estimate the prevalence and risk factors associated with tuberculosis (TB) among people living with human immunodeficiency virus (HIV) infection/acquired immunodeficiency syndrome (AIDS) in China. Methods A systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. After the literature was screened based on the inclusion and exclusion criteria, STATA® version 17.0 software was used for the meta-analysis. The heterogeneity among study data was assessed using I 2 statistics. Subgroup analysis and meta-regressions were performed to further explore the source of heterogeneity. Results A total of 5241 studies were retrieved. Of these, 44 studies were found to be eligible. The pooled prevalence of HIV/TB co-infection was 6.0%. The risk factors for HIV/TB co-infection included a low CD4+ T cell count, smoking, intravenous drug use and several other sociodemographic and clinical factors. Bacillus Calmette–Guérin (BCG) vaccination history was a protective factor. Conclusion A high prevalence of TB was observed among people living with HIV/AIDS in China. Low CD4+ T cell count, smoking, and intravenous drug use were the primary risk factors for HIV/TB co-infection, whereas BCG vaccination history was a protective factor. Checking for TB should be prioritized in HIV screening and healthcare access. Systematic review registration Registered on PROSPERO, Identifier: CRD42022297754. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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