| Autor: |
Yuan Wang, Jiaru Zhuang, Shan Wang, Yibo Wu, Ling Chen |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
PeerJ, Vol 12, p e17382 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2167-8359 |
| DOI: |
10.7717/peerj.17382 |
| Popis: |
Background Preoperative inflammatory factors and nutritional status are strongly associated with the prognosis of a variety of cancers. We explored the relationship between preoperative lymphocytes, neutrophils and albumin (LANR) and progression-free survival in breast cancer patients. Methods The clinical and follow-up data of 200 breast cancer patients were retrospectively analyzed in this study, and the value of LANR was determined as follows: LANR, lymphocytes × albumin/neutrophils. ROC curves, COX proportional risk regression analysis and subgroup analysis were used to assess the prognostic value of LANR in progression-free survival of breast cancer patients. Results The median age of the patients was 55.5 years (range 50–62 years). The median follow-up time was 46 months (range 33–55 months). In progression-free survival, the area under the LANR curve was 0.748 and the HR (95% CI) was 0.035 (0.679–0.817). LANR was associated with age (p = 0.02), positive axillary lymph nodes (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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