Centromeric enrichment of LINE-1 retrotraposon in two species of South American monkeys Alouatta belzebul and Ateles nancymae (Platyrrhini, Primates)
| Autor: | Francesca Dumas, Milioto Vanessa, Simona Ceraulo |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Caryologia (2022) |
| Druh dokumentu: | article |
| ISSN: | 0008-7114 2165-5391 |
| Popis: | LINE-1 are retrotransposable elements, a kind of repetitive DNA included in the heterochromatin regions of chromosomes. Repetitive DNA represent one of the major genomic components which role is not still clear challenging genomic assembly. LINE-1 sequences have been linked to genome evolution, plasticity and speciation; despite their importance their chromosomal distribution is poorly known in Primates. In this perspective, we mapped through fluorescence in situ hybridization LINE-1 probes onto two representative platyrrhini species, Aotus nancymae (Cebidae) and on Alouatta belzebul (Atelidae), both characterized to have a high rearranged karyotype, in order to investigate their chromosomal distribution and role and better characterize the two genomes. We find a centromeric enrichment of LINE-1 sequences on all biarmed and acrocentric chromosomes co-localize with heterochromatin C positive bands. This distribution let us to hypothesizes that LINE 1 sequences could have a role in centromere architecture and karyotype organization of platyrrhini genomes. |
| Databáze: | Directory of Open Access Journals |
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