Primary immunodeficiency in adults: total variable immune deficiency clinical manifestations, immunological and genetic defects, treatment

Autor: Aleksandr Viktorovich Karaulov, Irina Valentinovna Sidorenko, Vladimir Vladimirovich Androsov, Anna Sergeevna Kapustina, A V Karaulov, I V Sidorenko, V V Androsov, A S Kapustina
Jazyk: ruština
Rok vydání: 2011
Předmět:
Zdroj: Терапевтический архив, Vol 83, Iss 10, Pp 49-54 (2011)
Druh dokumentu: article
ISSN: 0040-3660
2309-5342
Popis: The most prevalent form of primary immunodeficiency with a total defect of antibody production in adults is common variable immunodeficiency (CVID). Compared to other forms of primary immunodeficiency, CVID is characterized by later onset of clinical manifestations represented by infectious, autoimmune and malignant diseases. To avoid development of complications and patient incapacitating, it is necessary to make an early diagnosis and initiate regular replacement therapy with intravenous immunoglobulins.
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