Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort study

Autor: Tavares Madede, Nilesh Bhatt, Edna Viegas, Arlete Mahumane, Gustavo Amorim, Adriana Santos, Américo Barata, João Luís Manuel, Caroline De Schacht, Edna Nhacule, Celso Belo, Peter W Young, Faustino Júnior, Eduarda Pimentel De Gusmão, Humberto Muquingue, Ana Muteerwa, Dulce Bila, Mohammed A Ouenzar, Reginalda Cumbane, Muhamad Ynusse, Paula Paulo, Ivete Meque, Dércio Menete, Kelvin Manuel, Unicia Chibale, Ouenzar Mohammed Ali, Nilzio Cavele, Sádia Pereira, Maria Enosse, Márcia Mutisse
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: BMJ Open, Vol 13, Iss 6 (2023)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2022-068988
Popis: Introduction As COVID-19 continues to spread globally and within Mozambique, its impact among immunosuppressed persons, specifically persons living with HIV (PLHIV), and on the health system is unknown in the country. The ‘COVid and hIV’ (COVIV) study aims to investigate: (1) the seroprevalence and seroincidence of SARS-CoV-2 among PLHIV and healthcare workers providing HIV services; (2) knowledge, attitudes, practices and perceptions regarding SARS-CoV-2 infection; (3) the pandemic’s impact on HIV care continuum outcomes and (4) facility level compliance with national COVID-19 guidelines.Methods and analysis A multimethod study will be conducted in a maximum of 11 health facilities across Mozambique, comprising four components: (1) a cohort study among PLHIV and healthcare workers providing HIV services to determine the seroprevalence and seroincidence of SARS-CoV-2, (2) a structured survey to assess knowledge, attitudes, perceptions and practices regarding COVID-19 disease, (3) analysis of aggregated patient data to evaluate retention in HIV services among PLHIV, (4) an assessment of facility implementation of infection prevention and control measures.Ethics and dissemination Ethical approval was obtained from the National Health Bioethics Committee, and institutional review boards of implementing partners. Study findings will be discussed with local and national health authorities and key stakeholders and will be disseminated in clinical and scientific forums.Trial registration number NCT05022407.
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