| Autor: |
Vanessa Fernández-Calleja, Pablo Hernández, Jorge B. Schvartzman, Mario García de Lacoba, Dora B. Krimer |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
PeerJ, Vol 5, p e3432 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2167-8359 |
| DOI: |
10.7717/peerj.3432 |
| Popis: |
Development of drug resistance limits the effectiveness of anticancer treatments. Understanding the molecular mechanisms triggering this event in tumor cells may lead to improved therapeutic strategies. Here we used RNA-seq to compare the transcriptomes of a murine erythroleukemia cell line (MEL) and a derived cell line with induced resistance to differentiation (MEL-R). RNA-seq analysis identified a total of 596 genes (Benjamini–Hochberg adjusted p-value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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