Mixed squamous – neuroendocrine carcinoma of the gallbladder: A case report of a rare pathological entity
| Autor: | Rohik Anjum T. Siddeek, Amit Gupta, Krishna Bhukya Sai, Edem Sanketh, Deepak Rajput, Sweety Gupta, Ravi Hari Phulware |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Cancer Research, Statistics, and Treatment, Vol 7, Iss 1, Pp 121-125 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2590-3233 2590-3225 |
| DOI: | 10.4103/crst.crst_186_23 |
| Popis: | Gallbladder cancers are the most common biliary tract malignancies in the world. Adenocarcinoma constitutes the most common histology in gallbladder cancer. Neuroendocrine neoplasms of the gallbladder account for about 0.5% of all neuroendocrine neoplasms and 2.1% of all gallbladder tumors. They are rare tumors and present with non-specific symptoms such as abdominal pain, weight loss, anorexia, and obstructive jaundice, and, therefore, are often challenging to diagnose and treat. Mixed neuroendocrine-non-neuroendocrine neoplasm is a subtype of neuroendocrine neoplasm. To add to the literature, we report a rare case of a patient who presented with pain in the abdomen and non-bilious vomiting and was diagnosed with mixed neuroendocrine-non-neuroendocrine gallbladder cancer, identified by immunohistochemistry, and treated with palliative chemotherapy. Due to non-specific symptoms, patients may present at an advanced stage. Further, immunohistochemistry may assist in clinching the diagnosis. |
| Databáze: | Directory of Open Access Journals |
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