| Autor: |
Marian Mikołaj Zgoda, Karolina Partyczyńska, Katarzyna Bujnicka, Justyna Aleksandra Kołodziejska, Sławomira Nowak, Zbigniew Marczyński, Magdalena Piechota-Urbańska, Beata Skibska, Andrzej Stańczak |
| Jazyk: |
polština |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Farmacja Polska, Vol 76, Iss 12, Pp 676-685 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
0014-8261 |
| DOI: |
10.32383/farmpol/132332 |
| Popis: |
Research studies have been performed on cosmetic creams for the treatment of acne, cleansing, bio-moisturizing and epidermis whitening as well as for reducing bacterial growth and preventing papulopustular lesions. There were used analytical methods recommended by the Polish Pharmacopoeia (PP X and XI) as well as Polish Standard (PN-ISO) for estimating morphological and pharmacotherapeutic properties of cosmetic preparations. The determined high content of water and volatile components allowed to determine the morphological structure of cosmetic creams. They are „HIPRE”- type hydrogel emulsions. The thermodynamic parameters of therapeutic agents and phytochemicals contained in plant extracts and essential oils (Ʃ∆Ei, Ʃ∆Vi, δ1/2, HLBRequ.) allowed to calculate the particle radius (r) with the bioavailability coefficient=1.0, owing to which the Einstein-Smoluchowski equation was solved in the application system (D= k·T/σπr·η). The practical viscosity determined by Casson’s method enabled to calculate the diffusion coefficient (D) and to estimate the proces of mass exchange at the phase boundary, which decides about the pharmacotherapeutic effectiveness of the tested preparations. The effective process of mass exchange at the phase boundary is evidenced by the calculated numerical values of the diffusion coefficients, and above all, the topological radius of diffusing molecules (r |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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