Analysis of controlled ovarian hyperstimulation protocols in women over 35 years old with poor ovarian response: a real-world study

Autor:	Xiaoyan Duan, Zhan Li, Mingming Li, Xing Ma
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Poor ovarian response Controlled ovarian hyperstimulation Age Assisted reproductive technology Real-world study Gynecology and obstetrics RG1-991
Zdroj:	BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-7 (2023)
Druh dokumentu:	article
ISSN:	1471-2393
DOI:	10.1186/s12884-023-06112-4
Popis:	Abstract The objective of this study was to investigate the optimal controlled ovarian hyperstimulation (COH) protocol for patients aged 35 and above with poor ovarian response (POR), utilizing real-world data. This retrospective cohort study examined clinical information from a total of 4256 patients between January 2017 and November 2022. The patients were categorized into three groups: modified GnRH agonist protocol (2116 patients), GnRH antagonist protocol (1628 patients), and Mild stimulation protocol (512 patients). Comparative analysis was conducted on clinical variables and pregnancy outcomes across the three groups. The GnRH agonist protocol was associated with a higher number of oocyte number (4.02 ± 2.25 vs. 3.15 ± 1.52 vs. 2.40 ± 1.26, p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/5bc6a44c38164c289dbdea2d2cee17f3 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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