Affibody-based molecular probe 99mTc-(HE)3ZHER2:V2 for non-invasive HER2 detection in ovarian and breast cancer xenografts

Autor: Hu Xianwen, Hu Hongyu, Li Dandan, Wang Pan, Cai Jiong
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Open Medicine, Vol 19, Iss 1, Pp 5361-6 (2024)
Druh dokumentu: article
ISSN: 2391-5463
DOI: 10.1515/med-2024-1027
Popis: This study aimed to assess the biodistribution and bioactivity of the affibody molecular probe 99mTc-(HE)3ZHER2:V2, prepared by genetic recombination, and to investigate its potential for targeted human epidermal growth factor receptor 2 (HER2) imaging in SKOV3 ovarian cancer and MDA-MB-361 breast cancer xenografts.
Databáze: Directory of Open Access Journals