Autor: |
Fahimeh Varzideh, Urna Kansakar, Kwame Donkor, Scott Wilson, Stanislovas S. Jankauskas, Pasquale Mone, Xujun Wang, Angela Lombardi, Gaetano Santulli |
Jazyk: |
angličtina |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Frontiers in Cardiovascular Medicine, Vol 9 (2022) |
Druh dokumentu: |
article |
ISSN: |
2297-055X |
DOI: |
10.3389/fcvm.2022.863238 |
Popis: |
After an ischemic injury, the heart undergoes a complex process of structural and functional remodeling that involves several steps, including inflammatory and fibrotic responses. In this review, we are focusing on the contribution of microRNAs in the regulation of inflammation and fibrosis after myocardial infarction. We summarize the most updated studies exploring the interactions between microRNAs and key regulators of inflammation and fibroblast activation and we discuss the recent discoveries, including clinical applications, in these rapidly advancing fields. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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