Neutrophil–lymphocyte ratio as a potential marker for differential diagnosis between spinal tuberculosis and pyogenic spinal infection

Autor:	Hao Liu, Yin Li, Jiang Yi, Wei Zhou, Shujie Zhao, Guoyong Yin
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	Neutrophil–lymphocyte ratio Spine tuberculosis Pyogenic spinal infection Differential diagnostic value Orthopedic surgery RD701-811 Diseases of the musculoskeletal system RC925-935
Zdroj:	Journal of Orthopaedic Surgery and Research, Vol 17, Iss 1, Pp 1-5 (2022)
Druh dokumentu:	article
ISSN:	1749-799X
DOI:	10.1186/s13018-022-03250-x
Popis:	Abstract Objective Distinguishing spinal tuberculosis and pyogenic spinal infection is extremely important. The neutrophil–lymphocyte ratio (NLR), a simple indicator, has been shown to be a novel inflammatory marker. The objective of our study was to determine whether the NLR could be a potential indicator for discriminating spinal tuberculosis (STB) from pyogenic spinal infection (PSI). Methods We compared the clinical and laboratory characteristics of 146 patients diagnosed with STB and 60 participants with PSI from the First Affiliated Hospital of Nanjing Medical University. The NLR's diagnostic ability for differential diagnosis was assessed and compared to other hematological indicators, including the platelet–lymphocyte ratio (PLR). Results The NLR in STB patients was considerably lower than that in PSI patients [3.85 (2.70–5.71) vs. 10.82 (6.79–17.62), P
Databáze:	Directory of Open Access Journals
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