Association of serum stromal cell-derived factor 1 levels with EZSCAN score and its derived indicators in patients with type 2 diabetes

Autor: Wang-shu Liu, Ling-yan Hua, Su-xiang Zhu, Feng Xu, Xue-qin Wang, Chun-feng Lu, Jian-bin Su, Feng Qi
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Endocrine Connections, Vol 11, Iss 4, Pp 1-7 (2022)
Druh dokumentu: article
ISSN: 2049-3614
DOI: 10.1530/EC-21-0629
Popis: Background: The aim of the study was to explore whether plasma stromal cel l-derived factor 1 (SDF-1) levels are associated with the EZSCAN score an d its derived indicators in patients with type 2 diabetes (T2D). Methods: From July 2020 to December 2020, a total of 253 patients with T2D were consecutively recruited. Serum SDF-1 levels were measured by sa ndwich ELISA. EZSCAN test was applied to evaluate the sudomotor function of each pat ient, and based on the results, EZSCAN score, cardiac autonomic neuropathy risk sc ore (CANRS) and cardiovascular risk score (CVDRS) were calculated by particular algorithms. In addition, other relevant clinical data were also collected. Results: With increasing tertiles of serum SDF-1 levels, the CANRS and CVDRS significantly increased (both P for trend
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