ASSESSMENT OF ANTIARRHYTHMIC ACTIVITY AND SAFETY OF NEW DERIVATIVES OF MORPHOLINOACETIC ACID
| Autor: | I. P. Rudakova, O. V. Gashkova |
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| Jazyk: | ruština |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Разработка и регистрация лекарственных средств, Vol 0, Iss 2, Pp 242-245 (2019) |
| Druh dokumentu: | article |
| ISSN: | 2305-2066 2658-5049 |
| Popis: | Study of the anti-arrhythmic influence of the new organic synthesis’s products was the purpose of an actual research. Such characteristics of these compounds as acute toxicity, anti-arrhythmic and pro-arrhythmic activity were studied. The mostly strongly marked effect was discovered while using M-0 and M-18. These compounds showed the highest anti-arrhythmic activity and the lowest toxicity. It was also discovered that M-18 compound is less dangerous than M-0 one due to absence of the certainly expressed spill-over effect of an arrhythmogenic action. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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