Biochemical spectrum of parathyroid hormone disorders in patients attending Tribhuvan University Teaching Hospital, Kathmandu, Nepal

Autor: Apeksha Niraula, Sujata Baidya, Vijay Kumar Sharma, Eans Tara Tuladhar, Raju Kumar Dubey, Aseem Bhattarai, Mithileshwer Raut, Naresh Parajuli
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: SAGE Open Medicine, Vol 11 (2023)
Druh dokumentu: article
ISSN: 2050-3121
20503121
DOI: 10.1177/20503121231182204
Popis: Objectives: This study intends to determine the association of parathormone with vitamin D and other biochemical parameters (calcium and phosphate) and evaluate the relationship between low vitamin D and parathormone levels. Methods: A hospital-based cross-sectional study was conducted among 310 study participants over the period of 1 year. Patients who underwent laboratory investigations for vitamin D, parathormone, calcium, and phosphate in the Clinical Biochemistry Laboratory at the Institute of Medicine, Tribhuvan University Teaching Hospital were included. Serum intact parathyroid hormone, vitamin D, calcium, and phosphate were measured in Abbott Architect (ci4100) integrated system autoanalyzer. Results: Among the 310 study participants, 177 (57%) were males and 43% were females. The mean age of the patient was 47.09 ± 19.01 years. High intact parathyroid hormone (>68 pg/ml) was observed in 73% of the patients. Low vitamin D (
Databáze: Directory of Open Access Journals