| Autor: |
Yasmine S. Zubi, Kosuke Seki, Ying Li, Andrew C. Hunt, Bingqing Liu, Benoît Roux, Michael C. Jewett, Jared C. Lewis |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-022-29239-y |
| Popis: |
Dynamic control over protein function is a central challenge in synthetic biology. Here the authors present an integrated computational and experimental workflow for engineering reversible protein switches; metal-chelating unnatural amino acids genetically encoded into two conformationally dynamic enzymes to yield robust switches. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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