Metabolic syndrome and insulin resistance in obese adolescents
| Autor: | Amanda Oliva Gobato, Ana Carolina J. Vasques, Mariana Porto Zambon, Antonio de Azevedo Barros Filho, Gabriel Hessel |
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| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Revista Paulista de Pediatria, Vol 32, Iss 1, Pp 55-59 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1984-0462 0103-0582 |
| DOI: | 10.1590/S0103-05822014000100010 |
| Popis: | Objective: To verify the prevalence of metabolic syndrome and insulin resistance in obese adolescents and its relationship with different body composition indicators. Methods: A cross-sectional study comprising 79 adolescents aged ten to 18 years old. The assessed body composition indicators were: body mass index (BMI), body fat percentage, abdominal circumference, and subcutaneous fat. The metabolic syndrome was diagnosed according to the criteria proposed by Cook et al. The insulin resistance was determined by the Homeostasis Model Assessment for Insulin Resistance (HOMA-IR) index for values above 3.16. The analysis of ROC curves was used to assess the BMI and the abdominal circumference, aiming to identify the subjects with metabolic syndrome and insulin resistance. The cutoff point corresponded to the percentage above the reference value used to diagnose obesity. Results: The metabolic syndrome was diagnosed in 45.5% of the patients and insulin resistance, in 29.1%. Insulin resistance showed association with HDL-cholesterol (p=0.032) and with metabolic syndrome (p=0.006). All body composition indicators were correlated with insulin resistance (p |
| Databáze: | Directory of Open Access Journals |
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