Polygenic contribution to the relationship of loneliness and social isolation with schizophrenia

Autor: Álvaro Andreu-Bernabeu, Covadonga M. Díaz-Caneja, Javier Costas, Lucía De Hoyos, Carol Stella, Xaquín Gurriarán, Clara Alloza, Lourdes Fañanás, Julio Bobes, Ana González-Pinto, Benedicto Crespo-Facorro, Lourdes Martorell, Elisabet Vilella, Gerard Muntané, Juan Nacher, María Dolores Molto, Eduardo Jesús Aguilar, Mara Parellada, Celso Arango, Javier González-Peñas
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-27598-6
Popis: Loneliness and social isolation (LNL-ISO) are associated with schizophrenia. Here the authors demonstrate the role of shared heritability, bidirectional causal relationships and significant differences by sex, illustrating the genomic footprint of social isolation on schizophrenia.
Databáze: Directory of Open Access Journals