| Autor: |
Karunakar Baikadi, Anil Talakokkula, A. Venkat Narsaiah |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
SynOpen, Vol 03, Iss 01, Pp 26-35 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2509-9396 |
| DOI: |
10.1055/s-0037-1611665 |
| Popis: |
Abstract The stereoselective total synthesis of Sch-725674 in 14 linear synthetic steps with 10.3% overall yield is described. The synthesis started from commercially available starting materials, d-ribose and (R)-benzyl glycidol. The key reactions involved CBS reduction, Julia–Kocienski olefination, Horner–Wadsworth–Emmons reaction, and Shiina macrolactonization. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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