The association between photoreceptor layer thickness measured by optical coherence tomography and visual sensitivity in glaucomatous eyes.

Autor: Ryo Asaoka, Hiroshi Murata, Mieko Yanagisawa, Yuri Fujino, Masato Matsuura, Tatsuya Inoue, Kenji Inoue, Junkichi Yamagami
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: PLoS ONE, Vol 12, Iss 10, p e0184064 (2017)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0184064
Popis: To assess the thickness of the photoreceptor layer in the macular region in glaucomatous eyes.Humphrey 10-2 visual field (VF) testing was carried out and mean threshold (mTH) was calculated in 118 eyes from 118 patients with open angle glaucoma. Macular optical coherence tomography (OCT) measurements (RS 3000, Nidek Co.ltd., Aichi, Japan) were also carried out in all eyes. Thickness measurements were recorded in the outer segment and retinal pigment epithelium (OS+RPE), the nerve fiber layer (NFL), the ganglion cell layer and inner plexiform layer (GCL+IPL), the inner nuclear layer and outer plexiform layer (INL+OPL) and the outer nuclear layer and inner segment (ONL+IS). The relationship between mTH and the thickness of these five different layers was investigated. Additionally, the influence of OS+RPE on mTH was investigated using partial correlation eliminating the effect of other variables of NFL, GCL+IPL, INL+OPL, ONL+IS, age, gender and axial length.The thickness of the OS+RPE layer was significantly decreased with the decrease of mTH (coefficient = 0.63 p
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