Aluminum Triflate—Catalyzed Adamantylation of N-Nucleophiles

Autor: Valery V. Konshin, Vitaly A. Shcherbinin, Ida A. Lupanova, Dzhamilya N. Konshina
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Proceedings, Vol 9, Iss 1, p 21 (2019)
Druh dokumentu: article
ISSN: 2504-3900
DOI: 10.3390/ecsoc-22-05661
Popis: An efficient method is proposed for N-adamantylation of primary carboxamides and sulfonamides, ethyl carbamate, and 4-nitroaniline using the stoichiometric amount of 1-adamantanol in the presence of 5 mol% aluminum triflate in nitromethane. Similarities and differences between adamantylation of some azoles catalyzed by aluminum triflate in nitromethane and the reaction catalyzed by Brønsted acids were revealed.
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