Risk of hospitalization and mortality associated with uncontrolled blood pressure in patients with hypertension and COVID-19

Autor: Jaejin An, Hui Zhou, Tiffany Q. Luong, Rong Wei, Matthew T. Mefford, Teresa N. Harrison, Ming-Sum Lee, John J. Sim, Jeffrey W. Brettler, John P. Martin, Angeline L. Ong-Su, Kristi Reynolds
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: International Journal of Cardiology. Cardiovascular Risk and Prevention, Vol 11, Iss , Pp 200117- (2021)
Druh dokumentu: article
ISSN: 2772-4875
DOI: 10.1016/j.ijcrp.2021.200117
Popis: Objective: The role of uncontrolled blood pressure (BP) in COVID-19 severity among patients with hypertension is unclear. We evaluated the association between uncontrolled BP and the risk of hospitalization and/or mortality in patients with hypertension from a large US integrated healthcare system. Methods: We identified patients with hypertension and a positive RT-PCR test result or a diagnosis of COVID-19 between March 1 – September 1, 2020 from Kaiser Permanente Southern California. BP categories was defined using the most recent outpatient BP measurement during 12 months prior to COVID-19 infection. The primary outcome of interest was all-cause hospitalization or mortality within 30 days from COVID-19 infection. Results: Among 12,548 patients with hypertension and COVID-19 (mean age = 60 years, 47% male), 63% had uncontrolled BP (≥130/80 mm Hg) prior to COVID-19. Twenty-one percent were hospitalized or died within 30 days of COVID-19 infection. Uncontrolled BP was not associated with higher hospitalization or mortality (adjusted rate ratios for BP ≥ 160/100 mm Hg vs
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