Reconstructive Peri-Implantitis Therapy by Using Bovine Bone Substitute with or without Hyaluronic Acid: A Randomized Clinical Controlled Pilot Study

Autor: Dragana Rakašević, Miodrag Šćepanović, Iva Mijailović, Tijana Mišić, Bojan Janjić, Ivan Soldatović, Aleksa Marković
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Functional Biomaterials, Vol 14, Iss 3, p 149 (2023)
Druh dokumentu: article
ISSN: 2079-4983
DOI: 10.3390/jfb14030149
Popis: Background: The present pilot study aimed to assess clinical and radiographic efficiencies of bovine bone substitute (BBS) merged with hyaluronic acid (HA) in peri-implantits reconstructive surgery. Methods: Peri-implantitis (diagnosed 6.03 ± 1.61 years of implant loading) bone defects were randomly treated either with BBS plus HA (test group) or BBS alone (control group). Clinical parameters including peri-implant probing depth (PPD), bleeding on probing (BOP), implant stability (ISQ), and radiographic changes in vertical and horizontal marginal bone (MB) levels were assessed at six months postoperatively. New temporary and permanent screw-retained crowns were made at two weeks and three months postoperatively. Data were analyzed using parametric and non-parametric tests. Results: In both groups, 75% of patients and 83% of implants achieved treatment success after six months (no BOP, PPD p < 0.05). The vertical MB gain was significantly greater in the test group compared to the control (p < 0.05). Conclusions: Short-term outcomes suggested that BBS merged with HA could improve clinical and radiographic outcomes in peri-implantitis reconstructive therapy.
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