Cerebral Sinus Venous Thrombosis due to Asparaginase Therapy

Autor:	Youssef Alsaid, Shamshad Gulab, Mohammed Bayoumi, Saleh Baeesa
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Case Reports in Hematology, Vol 2013 (2013)
Druh dokumentu:	article
ISSN:	2090-6560 2090-6579
DOI:	10.1155/2013/841057
Popis:	We report a 9-year-old boy with acute lymphoblastic leukemia (ALL) in high-risk group who suffered from left sided focal seizures and ipsilateral hemiparesis during his induction with Asparaginase chemotherapy. Superior sagittal sinus thrombosis and right frontal hemorrhage were demonstrated on brain magnetic resonance imaging (MRI) scans . Anticoagulation was initiated with unfractionated heparin and switched to low molecular weight heparin after 3 weeks and continued for 6 months. At one-year followup, he had complete response to chemotherapy for ALL, with residual mild left hemiparesis, and his MRI scans revealed recanalized venous sinuses. The case highlights the importance of considering cerebral venous thrombosis as a complication of Asparaginase therapy.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/cad5b5e9b29e424ca4f0429592d46ba8 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF