The Role of Immunotherapy in the Treatment of Rare Central Nervous System Tumors

Autor:	Andrew Rodriguez, Carlos Kamiya-Matsuoka, Nazanin K. Majd
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	immunotherapy treatment rare central nervous system tumors Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Current Oncology, Vol 30, Iss 6, Pp 5279-5298 (2023)
Druh dokumentu:	article
ISSN:	1718-7729 1198-0052
DOI:	10.3390/curroncol30060401
Popis:	Establishing novel therapies for rare central nervous system (CNS) tumors is arduous due to challenges in conducting clinical trials in rare tumors. Immunotherapy treatment has been a rapidly developing field and has demonstrated improvements in outcomes for multiple types of solid malignancies. In rare CNS tumors, the role of immunotherapy is being explored. In this article, we review the preclinical and clinical data of various immunotherapy modalities in select rare CNS tumors, including atypical meningioma, aggressive pituitary adenoma, pituitary carcinoma, ependymoma, embryonal tumor, atypical teratoid/rhabdoid tumor, and meningeal solitary fibrous tumor. Among these tumor types, some studies have shown promise; however, ongoing clinical trials will be critical for defining and optimizing the role of immunotherapy for these patients.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/5b3ffda32b984ff381bedc6892b0f53e Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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