Decreasing Risk of Fatal Subarachnoid Hemorrhage and Other Epidemiological Trends in the Era of Coiling Implementation in Australia

Autor: John Mark Worthington, Chris Goumas, Bin Jalaludin, Melina Gattellari
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Frontiers in Neurology, Vol 8 (2017)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2017.00424
Popis: Background and purposeSubarachnoid hemorrhage (SAH) is associated with a high risk of mortality and disability in survivors. We examined the epidemiology and burden of SAH in our population during a time services were re-organized to facilitate access to evidence-based endovascular coiling and neurosurgical care.MethodsSAH hospitalizations from 2001 to 2009, in New South Wales, Australia, were linked to death registrations to June 30, 2010. We assessed the variability of admission rates, fatal SAH rates and case fatality over time and according to patient demographic characteristics.ResultsThere were 4,945 eligible patients admitted to hospital with SAH. The risk of fatal SAH significantly decreased by 2.7% on average per year (95% CI = 0.3–4.9%). Case fatality at 2, 30, 90, and 365 days significantly declined over time. The average annual percentage reduction in mortality ranged from 4.4% for 30-day mortality (95% CI −6.1 to −2.7) (P
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