Electrochemical carbon fiber-based technique for simultaneous recordings of brain tissue PO2, pH, and extracellular field potentials

Autor: Patrick S. Hosford, Jack A. Wells, Isabel N. Christie, Mark F. Lythgoe, Julian Millar, Alexander V. Gourine
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Biosensors and Bioelectronics: X, Vol 3, Iss , Pp 100034- (2019)
Druh dokumentu: article
ISSN: 2590-1370
DOI: 10.1016/j.biosx.2020.100034
Popis: A method for simultaneous electrochemical detection of brain tissue PO2 (PtO2) and pH changes together with neuronal activity using a modified form of fast cyclic voltammetry with carbon fiber electrodes is described. This technique has been developed for in vivo applications and recordings from discrete brain nuclei in experimental animals. The small size of the carbon fiber electrode (⌀7 μm, length
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