Parkinson's disease: Impact of clinical and cognitive aspects on quality of life

Autor: Glória Maria Almeida Souza Tedrus, Lineu Correa Fonseca, Patrícia Mencaroni Kange
Jazyk: angličtina
Předmět:
Zdroj: Dementia & Neuropsychologia, Vol 4, Iss 2, Pp 131-137
Druh dokumentu: article
ISSN: 1980-5764
DOI: 10.1590/S1980-57642010DN40200010
Popis: Abstract Parkinson's disease (PD) is a chronic disease manifested principally by motor signs and symptoms, but with frequent neuropsychological alterations. Objectives: To study the relationship between clinical and cognitive aspects and the perception of quality of life (QOL) in PD patients. Methods: Twenty consecutive patients (13 men) with idiopathic PD (mean age: 64.5y), mean disease time of 7.8 years and at stages 1-3 according to the modified Hoehn and Yahr staging scale (HYS), all outpatients from the Neurology Department of the Celso Pierro General and Maternity Hospital (PUC-Campinas), were analyzed. The following were applied: a clinical-neurological assessment, the Mini-Mental State Examination (MMSE), standard neuropsychological battery of the CERAD (Consortium to Establish a Registry for Alzheimer's Disease), Hamilton Depression Rating Scale (HAM-D) and a QOL questionnaire (Parkinson's Disease Questionnaire - PDQ-39). Statistical analysis was carried out at a significance level of p
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