Efficacy of insulin lispro in improving glycemic control in gestational diabetes
| Autor: | M C Deepaklal, Kurian Joseph, Rekha Kurian, Nandita A Thakkar |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Indian Journal of Endocrinology and Metabolism, Vol 18, Iss 4, Pp 491-495 (2014) |
| Druh dokumentu: | article |
| ISSN: | 2230-8210 2230-9500 |
| DOI: | 10.4103/2230-8210.137492 |
| Popis: | Aim: To assess the safety and efficacy of insulin lispro in improving glycemic control in patients with gestational diabetes. Materials and Methods: A retrospective observational study was conducted at a single center on 201 gestational women with diabetes. Subjects who received insulin lispro performed blood glucose self-monitoring and recorded the readings in the fasting state and 1 h after each meal. At each contact (in person or telephonic contact), the insulin dose was adjusted based on the readings measured. A total of 53 subjects also recorded glucose levels post-partum. Pregnancy and post-delivery glucose level and insulin requirements of these 53 patients were compared. Results: Analysis of glucose levels both fasting and post-prandial glucose levels revealed that after using insulin lispro, the number of episodes of post-prandial hyperglycemia (1 h plasma glucose >120 mg/dL) was minimal and so was the incidence of hypoglycemia. Hypoglycemia was defined as a blood sugar value of. There was neither any congenital abnormality except for a poorly formed pinna in the right ear of one baby nor any post-partum complications of note. Conclusion: Insulin lispro is an effective and safe treatment option in gestational diabetes. |
| Databáze: | Directory of Open Access Journals |
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