| Autor: |
A. Sultan, F. Khan, A. Nadeem, M. Shah, H. Khan, Z. Rehman |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
International Journal of Infectious Diseases, Vol 130, Iss , Pp S29-S30 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
1201-9712 |
| DOI: |
10.1016/j.ijid.2023.04.068 |
| Popis: |
Intro: Carbepenems resistance(CRE) among microorganisms is a global public-health problem with limited treatment options Asymptomatic gastrointestinal carriage of CRE in ICU patients is common and may be associated with increased risk of CRE infection. Methods: The cross-sectional hospital based study was done to evaluate the prevalence of CRE colonization and hospital care associated infection(HCAI) in ICU patients. Per-rectal swabs of patients were collected within 24 hours of admission and patients were followed up weekly for CRE colonization and for development of HCAI until discharge/transfer from the ICU. Samples processing, identification of isolates was done as per standard microbiological techniques. Antibiotic susceptibility & phenotypic screening and confirmation for MBL producers was done as per CLSI guidelines. Detection of bla genes (blaNDM, blaVIM, blaOXA, blaKPC, blaIMP) was done by multiplex Polymerase Chain Reaction. Findings: Total 120 patients were admitted in ICU during the study period. Of these 45(37.9%) patients were found to be colonized with CRE within 24 hours of their admission. Duration of hospital stay(n=24; 53.3%, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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