Mean platelet volume as diagnostic and therapeutic marker of risk and prognosis of heart disease

Autor: Henshaw Uchechi Okoroiwu, Christopher Ogar Ogar
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Italian Journal of Medicine, Vol 12, Iss 1, Pp 10-14 (2018)
Druh dokumentu: article
ISSN: 1877-9344
1877-9352
DOI: 10.4081/itjm.2018.918
Popis: Increased mean platelet volume (MPV) is associated with platelet reactivity and is a predictor of cardiovascular risk and unprovoked nervous thromboembolism. Mean platelet volume is a precise measure of platelet size. Studies have reported the use of MPV as a biomarker for predicting ischemic stroke in atrial fibrillation patients as well as in anticoagulant prescription and rhythm-control therapy. Moreover, MPV may predict cardiovascular event outcome following percutaneous coronary intervention in patients with coronary artery disease. MPV may predict residual platelet reactivity in dual antiplatelet therapy. Factors influencing MPV result were discussed. This review centered on the reports that MPV may be a biomarker of risk and prognosis of prevalent heart diseases.
Databáze: Directory of Open Access Journals