Microwave Accelerated Aza-Claisen Rearrangement

Autor: Eva Gajdošíková, Miroslava Martinková, Jozef Gonda, Patrik Conka
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Molecules, Vol 13, Iss 11, Pp 2837-2847 (2008)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules131102837
Popis: A study of microwave-induced and standard thermal Overman rearrangement of selected allylic trichloroacetimidates 1a-1f, 6-8 to the corresponding acetamides 2a-2f, 9-11 is reported. The microwave-assisted rearrangement of trifluoroacetimidate 13 is also described. Using this methodology, an efficient access to versatile allylic trihaloacetamides building synthons was established.
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