Impact of Postresuscitative Endogenous Intoxication on Lipid Peroxidation Processes in the Experiment

Autor: D. A. Yenikeyev, Ye. A. Nurgaleyeva, A. F. Samigullina, Yu. L. Baimurzina, M. A. Aleksandrov
Jazyk: English<br />Russian
Rok vydání: 2006
Předmět:
Zdroj: Общая реаниматология, Vol 2, Iss 6, Pp 111-114 (2006)
Druh dokumentu: article
ISSN: 1813-9779
2411-7110
DOI: 10.15360/1813-9779-2006-6-111-114
Popis: Endogenous intoxication and free radical oxidation were studied in rats after 10-minute clinical death due to systemic circulatory arrest. There were qualitative and quantitative changes in toxic substances throughout a 35-day postresuscitative period, as well as increased free radical oxidation processes in the vital organs (brain, liver, kidneys). At the same time, plasma samples showed inhibited chemiluminescence along with the elevated levels of low and medium molecular-weight substances since medium-weight molecules bound ferrous iron ions that were added to induce luminescence. The chemilu-minescence technique may serve as a rapid method for evaluating the degree of endogenous intoxication.
Databáze: Directory of Open Access Journals