Association between non-HDLC and 1-year prognosis in patients with spontaneous intracerebral haemorrhage: a prospective cohort study from 13 hospitals in Beijing

Autor: Yu Wang, Xingquan Zhao, Anxin Wang, Jianwei Wu, Wenjuan Wang, Ruixuan Jiang
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: BMJ Open, Vol 12, Iss 11 (2022)
Druh dokumentu: article
ISSN: 2044-6055
DOI: 10.1136/bmjopen-2022-061241
Popis: Objectives Previous studies suggested an inverse association between lipoprotein cholesterols and bleeding risk, while limited data were available about the predictive value of lipoproteins on intracerebral haemorrhage (ICH). Our recent research series showed that higher non-high-density lipoprotein cholesterol (non-HDLC) was an independent predictor of favourable 3-month outcome in ICH patients, we thus aimed to further investigate the association between non-HDLC levels and 1-year functional outcomes after ICH.Design Prospective multicentre cohort study.Setting 13 hospitals in Beijing, China.Participants A total of 666 ICH patients were included between December 2014 and September 2016.Methods Non-HDLC was calculated by subtracting HDL-C from total cholesterol. Patients were then grouped by non-HDLC levels into three categories:
Databáze: Directory of Open Access Journals