A case of microscopic polyangiitis with interstitial pneumonia after coronavirus disease-2019 infection, evidenced by positivity for multiple autoantibodies
| Autor: | Naoto Arai, Toshikazu Takasaki, Masashi Bando, Kei Yaoita, Yutaro Ueki, Shu Hisata, Makoto Maemondo |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: |
evere acute respiratory syndrome-coronavirus 2
Anti-neutrophil cytoplasmic antibody-associated vasculitis Myeloperoxidase-anti-neutrophil cytoplasmic antibody Anti-melanoma differentiation-associated gene 5 Anti-aminoacyl transfer RNA synthetase antibodies Diseases of the respiratory system RC705-779 |
| Zdroj: | Respiratory Medicine Case Reports, Vol 51, Iss , Pp 102103- (2024) |
| Druh dokumentu: | article |
| ISSN: | 2213-0071 |
| DOI: | 10.1016/j.rmcr.2024.102103 |
| Popis: | Anti-neutrophil cytoplasmic antibody-associated vasculitis is triggered by infection, dust exposure, and drugs. A 73-year-old male presented with dyspnea. Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) infection was confirmed upon admission. Exacerbation of interstitial pneumonia and renal dysfunction were observed. Analysis revealed positivity for myeloperoxidase-anti-neutrophil cytoplasmic antibody, other anti-aminoacyl transfer RNA synthetase antibodies, and anti-melanoma differentiation-associated gene 5. Renal biopsy confirmed crescentic glomerulonephritis, leading to the diagnosis of microscopic polyangiitis. Combination therapy with prednisolone and cyclophosphamide was initiated, resulting in improved respiratory and renal failure. There is a potential association between SARS-CoV-2 infection and the onset of autoimmune diseases. |
| Databáze: | Directory of Open Access Journals |
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