The effects of transurethral resection of the prostate on morbidity and mortality in patients with nondialysis-requiring renal insufficiency

Autor: Alp Ozgur Akdemir, Cetin Volkan Oztekin, Omer Gokhan Doluoglu, Mehmet Karabakan, Ozgur Ugurlu, Mesut Cetinkaya
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Therapeutic Advances in Urology, Vol 4 (2012)
Druh dokumentu: article
ISSN: 1756-2872
1756-2880
17562872
DOI: 10.1177/1756287211435088
Popis: Objectives : To compare the prevalence of preoperative co-morbid factors and complications of transurethral resection of prostate (TUR-P) in patients with normal and non-dialysis requiring elevated serum creatinine levels. Methods : The records of 357 consecutive patients with IPSS≥20, serum creatinine level ≤ 3 mg/dl, residual urine volume ≤ 300 ml and with no upper urinary tract dilatation or evidence of prostate cancer that underwent TUR-P were retrospectively evaluated. 60 patients who did not fulfill the inclusion criteria were excluded. The preoperative Na, K, creatinine levels and the early changes observed in these parameters after TUR-P of the patients with normal (Group1, n = 272) and elevated (Group2, n = 25) serum creatinine levels, as well as the preoperative baseline data and postoperative complications were compared. Results : Preoperative PSA, serum urea, creatinine and K levels were significantly higher in group2. No significant differences were observed between early and late postoperative complications of the two groups. Co-morbid diseases were significantly more common in group2. No progression in renal failure or de novo need for hemodialysis was observed in group2. Conclusions : TUR-P can be safely performed in BPH patients with mild serum creatinine elevations (1.6-3 mg/dl) and moderately increased prostate volumes without additional morbidity and mortality.
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