Allergic Contact Cell-Mediated Hypersensitivity in Psoriasis: A Narrative Minireview

Autor: Ana Maria Alexandra Stănescu, Ana-Maria-Antoaneta Cristea, Gabriel Cristian Bejan, Mariana Vieru, Anca Angela Simionescu, Florin-Dan Popescu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Medicina, Vol 58, Iss 7, p 914 (2022)
Druh dokumentu: article
ISSN: 1648-9144
1010-660X
DOI: 10.3390/medicina58070914
Popis: The dysfunctionality of the protective skin barrier in psoriasis allows easier cutaneous penetration of various contact haptens; thus, such patients can develop allergic contact hypersensitivity as a comorbidity. Both skin conditions involve T-cell-mediated mechanisms. Dermatologists and allergists should consider assessing allergic contact cell-mediated hypersensitivity in selected psoriasis patients, especially those with palmoplantar psoriasis and who are refractory to topical treatments, and in patients with psoriasis, with or without arthritis, treated with biologics that present skin lesions clinically suggestive of contact dermatitis.
Databáze: Directory of Open Access Journals