Clinical implications of prolonged hyperglycaemia before basal insulin initiation in type 2 diabetes patients: An electronic medical record database analysis

Autor:	Denis Raccah, Bruno Guerci, Mayank Ajmera, Keith Davis, Juliana Meyers, Elisheva Lew, Alka Shaunik, Lawrence Blonde
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	basal insulin clinical inertia glycaemic control treatment intensification type 2 diabetes Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Endocrinology, Diabetes & Metabolism, Vol 2, Iss 3, Pp n/a-n/a (2019)
Druh dokumentu:	article
ISSN:	2398-9238
DOI:	10.1002/edm2.61
Popis:	Summary Aims To assess the effect of duration of hyperglycaemia before basal insulin (BI) initiation on clinical outcomes in type 2 diabetes (T2D). Materials and methods Patients with T2D who initiated BI during 2009‐2013, had continuous enrolment for ≥2 years preceding and ≥1 year following BI initiation (“index date”), and had ≥1 glycated haemoglobin (A1C) measure not at target (ie, ≥7.0%) within 6 months preindex date were included in the study. Patients were stratified by preindex‐date duration of A1C ≥7.0%. Longitudinal A1C, weight, BMI, and diabetes medication were compared between cohorts for up to 15‐month follow‐up. Results Of 37 053 patients who initiated BI, 40.7%, 15.3%, 16.0%, and 28.0%, respectively, had uncontrolled A1C for
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/aa5a8182fe404f4b976da530ff15d82c Zobrazit plný text záznamu Plný text View record in DOAJ