| Autor: |
Karina F. Zoccal, Carlos A. Sorgi, Juliana I. Hori, Francisco W. G. Paula-Silva, Eliane C. Arantes, Carlos H. Serezani, Dario S. Zamboni, Lúcia H. Faccioli |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/ncomms10760 |
| Popis: |
Scorpion venom causes thousands of deaths worldwide. Here the authors show that the envenomation acts via prostaglandin E2 leading to inflammasome activation and lung pathology, counterbalanced by inflammation-limiting LTB4, and that COX inhibitors or exogenous LTB4 rescue the venom-induced mortality in mice. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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