The CAMH Neuroinformatics Platform: A Hospital-Focused Brain-CODE Implementation

Autor: David J. Rotenberg, Qing Chang, Natalia Potapova, Andy Wang, Marcia Hon, Marcos Sanches, Nikola Bogetic, Nathan Frias, Tommy Liu, Brendan Behan, Rachad El-Badrawi, Stephen C. Strother, Susan G. Evans, Jordan Mikkelsen, Tom Gee, Fan Dong, Stephen R. Arnott, Shuai Laing, Moyez Dharsee, Anthony L. Vaccarino, Mojib Javadi, Kenneth R. Evans, Damian Jankowicz
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Frontiers in Neuroinformatics, Vol 12 (2018)
Druh dokumentu: article
ISSN: 1662-5196
DOI: 10.3389/fninf.2018.00077
Popis: Investigations of mental illness have been enriched by the advent and maturation of neuroimaging technologies and the rapid pace and increased affordability of molecular sequencing techniques, however, the increased volume, variety and velocity of research data, presents a considerable technical and analytic challenge to curate, federate and interpret. Aggregation of high-dimensional datasets across brain disorders can increase sample sizes and may help identify underlying causes of brain dysfunction, however, additional barriers exist for effective data harmonization and integration for their combined use in research. To help realize the potential of multi-modal data integration for the study of mental illness, the Centre for Addiction and Mental Health (CAMH) constructed a centralized data capture, visualization and analytics environment—the CAMH Neuroinformatics Platform—based on the Ontario Brain Institute (OBI) Brain-CODE architecture, towards the curation of a standardized, consolidated psychiatric hospital-wide research dataset, directly coupled to high performance computing resources.
Databáze: Directory of Open Access Journals