Metabolic features of adiposity and glucose homoeostasis among school-aged inuit children from Nunavik (Northern Quebec, Canada)
| Autor: | Thierry Comlan Marc Medehouenou, Cynthia Roy, Pierre-Yves Tremblay, Audray St-Jean, Salma Meziou, Gina Muckle, Pierre Ayotte, Michel Lucas |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | International Journal of Circumpolar Health, Vol 80, Iss 1 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2242-3982 22423982 |
| DOI: | 10.1080/22423982.2020.1858605 |
| Popis: | In contrast to most Indigenous people in Canada, Inuit appeared until recently to have been protected from type 2 diabetes (T2D) related to obesity. We assessed the associations of metabolites (amino acids, acylcarnitines) with adiposity and biomarkers of T2D in school-aged Inuit children of Nunavik (Canada). Concentrations of metabolite were measured in plasma samples from a cross-sectional analysis of 248 children (mean age = 10.8 years). We assessed associations of plasma metabolites with adiposity measures (BMI, skinfold thicknesses) and T2D markers (insulin, glucose, adiponectin). Plasma concentrations of valine and tyrosine were higher in obese and overweight children compared to those of normal weight children (P |
| Databáze: | Directory of Open Access Journals |
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