| Autor: |
Seyed Abbas Mirmalek, Tina Parsa, Yekta Parsa, Soheila Yadollah-Damavandi, Seyed Alireza Salimi-Tabatabaee, Ehsan Jangholi, Sahar Hosseini, Soheil Ashkani-Esfahani, Hanieh Abooghadareh, Erfan Haghighifard |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Bangladesh Journal of Pharmacology, Vol 11, Iss 1 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
1991-0088 |
| DOI: |
10.3329/bjp.v11i1.23906 |
| Popis: |
Iris florentina is an ancient herbal remedy which was prescribed by many physicians due to its positive effects on dermatological problems, specifically skin wounds. Hence, we aimed to investigate the effects of this agent on full-thickness excisional skin wounds in laboratory rats. Three groups of rats (180 ± 20 g; n=8) with 1 cm diameter full-thickness excisional skin wound received daily treatment with I. florentina 10% ointment, and a group with no treatment. By using histomorphometrical methods, the amount of fibroblast population, collagen bundle synthesis, and vascularization (length density, mean diameter and volume density of the vessels) were estimated. Outcome of the study exhibited that the increase in fibroblast proliferation rate, collagen bundle synthesis, vascular density and vascular mean diameter in I. florentina-treated group were significant in comparison to the untreated group (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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