Treatment of spasticity in children and adolescents with cerebral palsy in Northern Europe: a CP-North registry study

Autor: Gunnar Hägglund, Sandra Julsen Hollung, Matti Ahonen, Guro L. Andersen, Guðbjörg Eggertsdóttir, Mark S. Gaston, Reidun Jahnsen, Ira Jeglinsky-Kankainen, Kirsten Nordbye-Nielsen, Ilaria Tresoldi, Ann I. Alriksson-Schmidt
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMC Neurology, Vol 21, Iss 1, Pp 1-12 (2021)
Druh dokumentu: article
ISSN: 1471-2377
DOI: 10.1186/s12883-021-02289-3
Popis: Abstract Background Spasticity is present in more than 80% of the population with cerebral palsy (CP). The aim of this study was to describe and compare the use of three spasticity reducing methods; Botulinum toxin-A therapy (BTX-A), Selective dorsal rhizotomy (SDR) and Intrathecal baclofen therapy (ITB) among children and adolescents with CP in six northern European countries. Methods This registry-based study included population-based data in children and adolescents with CP born 2002 to 2017 and recorded in the follow-up programs for CP in Sweden, Norway, Denmark, Iceland and Scotland, and a defined cohort in Finland. Results A total of 8,817 individuals were included. The proportion of individuals treated with SDR and ITB was significantly different between the countries. SDR treatment ranged from 0% ( Finland and Iceland) to 3.4% (Scotland) and ITB treatment from 2.2% (Sweden) to 3.7% (Denmark and Scotland). BTX-A treatment in the lower extremities reported 2017–2018 ranged from 8.6% in Denmark to 20% in Norway (p
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