| Autor: |
A. Scotto Rosato, S. Montefusco, C. Soldati, S. Di Paola, A. Capuozzo, J. Monfregola, E. Polishchuk, A. Amabile, C. Grimm, A. Lombardo, M. A. De Matteis, A. Ballabio, D. L. Medina |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-019-13572-w |
| Popis: |
It was known that prolonged TRMPL1 activation induces TFEB translocation and upregulates autophagic gene regulation. Here, the authors show that acute TRMPL1 activation also induces autophagy through VPS34 and by lysosomal calcium release independent of TFEB. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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