Pulmonary embolism induces pneumonia‐like lung injury beyond pulmonary infarction

Autor: Yue Wang, Bo Liu, Chuming Zhou, Yuan Wang, Jianing Miao, Li Zhao
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Pulmonary Circulation, Vol 13, Iss 4, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2045-8940
DOI: 10.1002/pul2.12322
Popis: Abstract Patients with pulmonary embolism (PE) commonly manifest concomitant “pneumonia,” which is generally believed to be either a cause (infection) or a consequence (infarction) of PE. This study aimed to clarify the relationship between PE and “pneumonia‐like” lesions beyond pulmonary infection and infarction. Chest computed tomography (CT) images of patients with PE and deep vein thrombosis (DVT) were retrospectively analyzed to compare the incidence of pneumonia lesions. The pathological damage and wet/dry ratio of lung tissues were observed in PE rats and PE plasma‐injected rats. In total, 793 and 914 inpatients were enrolled in the PE and DVT groups, respectively. Pneumonia lesions were observed in 36.9% and 26.3% of patients in the PE and DVT groups, respectively (p
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