Protective Effect of Capsicum Frutescens on Contractile Reactivity of Streptozotocin-Diabetic Rats
| Autor: | Farshad Roghani-Dehkordi, Mehrdad Roghani, Tourandokht Baluchnejadmojarad |
|---|---|
| Jazyk: | perština |
| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | پزشکی بالینی ابن سینا, Vol 12, Iss 2, Pp 5-9 (2005) |
| Druh dokumentu: | article |
| ISSN: | 2588-722X 2588-7238 |
| Popis: | Introduction & Objective : Considering the higher incidence of atherosclerosis and cardiovascular disorders in diabetes mellitus, this study was conducted to evaluate the effect of oral one-month administration of red pepper (Capsicum frutescens) on the contractile reactivity of isolated aorta in diabetic rats. Materials & Methods : For this purpose, male Wistar rats(n=32) were randomly divided into control, pepper-treated control, diabetic, and pepper-treated diabetic groups. For induction of diabetes, streptozotcin (STZ) was intraperitoneally administered (60 mg/Kg). Pepper-treated groups received pepper mixed with standard pelleted food at a weight ratio of 1/15. After one month, contractile reactivity of aortic rings to KCl and noreadrenaline was determined using isolated tissue setup. Results : Serum glucose level showed a significant increase in diabetic group at 2nd and 4th weeks (P |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|