Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation

Autor: Woo Yeong Park, Seong Sik Kang, Sung Bae Park, Ui Jun Park, Hyong Tae Kim, Won Hyun Cho, Seungyeup Han
Jazyk: English<br />Korean
Rok vydání: 2016
Předmět:
Zdroj: Kidney Research and Clinical Practice, Vol 35, Iss 1, Pp 50-54 (2016)
Druh dokumentu: article
ISSN: 2211-9132
DOI: 10.1016/j.krcp.2015.11.001
Popis: Background: Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-compatible (ABOc) and ABO-incompatible (ABOi) spousal donor KTs. Methods: Thirty-two cases of spousal donor KT performed from January 2011 to August 2013 were analyzed retrospectively. Twenty-one ABOc KTs and 11 ABOi KTs were performed. We investigated patient survival, graft survival, acute rejection, graft function, and complications. Results: During follow-up, patient and graft survival rates were 100% in both groups. There were no significant differences in the incidence of delayed graft function, acute rejection, and the change in graft function between the 2 groups. Medical and surgical complications were not significantly different between the groups. Conclusion: The clinical outcomes of ABOc and ABOi spousal donor KTs were equivalent. In ABOi KT, an emotionally motivated spousal donor KT may be a good alternative to the problem of the absolute shortage of kidney donations.
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